Viromer ® BLUE was developed for the siRNA transfection and is optimized for binding the size of small oligonucleotides like miRNA and siRNA. It is based on a medium sized branched polymer and the neutral charge of Viromer BLUE : miRNA and siRNA transfection complexes results in no aggregation and high performance in suspension cells like primary microglia cells. Viromer ® BLUE achieves the best miRNA or siRNA transfection results in classical cell lines widely used in cell biology such as HEK-293, HeLa and CHO as well as in challenging primary cells like mesenchymal stem cells, macrophages, monocytes, myoblasts and hepatocytes. By using Viromer ® BLUE a highly efficient miRNA and siRNA transfection is possible without the use of enhancers. Based on an active endosome escape mechanism siRNA transfection becomes more efficient compared to standard reagents as more of introduced siRNA/miRNA molecules reach the cytoplasma. Due to lowest toxicity and superior efficiency, Viromer ® BLUE turns a hardly-possible miRNA and siRNA transfection into a superior one.
What is it? An anabolic steroid (a steroid that acts as the hormone testosterone) that occurs in small amounts in the human body.
Medical Use: Used to treat osteoporosis in postmenopausal women, to aid in the growth of blood cells in bone marrow, and to help tissue and muscle growth in people suffering from degenerative diseases like AIDS.
Athletic Use: To grow muscle mass and aid in physical recovery from workouts.
Possible Negative Side Effects: Cardiovascular damage, sexual dysfunction, liver damage, acne, sterility, baldness, enlarged prostate.
Is it legal? Available only by prescription.
Cortisol is produced in the human body by the adrenal gland in the zona fasciculata,  the second of three layers comprising the adrenal cortex . The cortex forms the outer "bark" of each adrenal gland, situated atop the kidneys. The release of cortisol is controlled by the hypothalamus, a part of the brain. The secretion of corticotropin-releasing hormone by the hypothalamus  triggers cells in the neighboring anterior pituitary to secrete another hormone, the adrenocorticotropic hormone (ACTH), into the vascular system, through which blood carries it to the adrenal cortex. ACTH stimulates the synthesis of cortisol, glucocorticoids, mineralocorticoids, and dehydroepiandrosterone .